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Updated: Aug 9, 2026

A Rat Model of EcoHIV Brain Infection
Published on: January 21, 2021
New-onset seizures associated with HIV infection
1Neurology Unit, Department of Medicine, Chris Hani Baragwanath Hospital, and the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Abstract:
The authors studied new-onset seizures in 60 heterosexual black South African HIV-infected patients who had not used IV drugs. An intracranial space-occupying lesion was identified in 53% of patients, meningitis in 22%, and no additional cause in 25%. Of the patients with an identifiable cause, 64% had probable tuberculosis (tuberculoma or tuberculous meningitis). The majority of patients had late-stage HIV infection (CD4 counts <200/mm(3)).
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