Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The aged cardiovascular risk patient.

H J Priebe1

  • 1Department of Anaesthesia, University Hospital, Freiburg, Germany.

British Journal of Anaesthesia
|November 30, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Revised ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management. Implications for preoperative clinical evaluation.

Minerva anestesiologica·2014
Same author

Cricoid pressure: an expert's opinion.

Minerva anestesiologica·2009
Same author

Protective effects of inhaled carbon monoxide in pig lungs during cardiopulmonary bypass are mediated via an induction of the heat shock response.

British journal of anaesthesia·2009
Same author

Electrical impedance tomography to confirm correct placement of double-lumen tube: a feasibility study.

British journal of anaesthesia·2008
Same author

Costs of anaesthesia.

European journal of anaesthesiology·2005
Same author

[Acute anemia and risk patients: the heart].

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS·2001

Advanced age independently predicts adverse perioperative cardiac outcomes due to physiological decline and increased disease burden. Understanding age-related cardiovascular changes is crucial for managing perioperative risk in elderly patients.

Area of Science:

  • Cardiovascular Physiology
  • Geriatric Medicine
  • Perioperative Medicine

Background:

  • Healthy aging differs from age-related cardiovascular disease, though both impact cardiac function.
  • Biological age reflects interactions between aging and disease, affecting overall organ function.
  • Age-related cardiovascular changes, independent of disease, alter cardiac performance at rest and during stress.

Purpose of the Study:

  • To highlight age-related cardiovascular changes impacting perioperative management.
  • To identify key factors contributing to increased perioperative risk in the elderly.
  • To emphasize the independent role of advanced age in predicting adverse cardiac outcomes.

Main Methods:

  • Review of age-related alterations in cardiovascular structure and function.

Related Experiment Videos

  • Analysis of factors influencing cardiovascular performance (heart rate, contractility, etc.).
  • Identification of key age-related changes relevant to perioperative care (stiffened myocardium, blunted beta-receptor response, impaired autonomic control).

    • Main Results:

    • Advanced age is associated with a decline in resting organ function and reduced reserve capacity.
    • Aging exacerbates chronic diseases, further limiting functional reserve and increasing cardiovascular risk.
    • Increased medication use and altered pharmacokinetics/pharmacodynamics in the elderly raise the incidence of adverse reactions.

    Conclusions:

    • Advanced age is an independent predictor of adverse perioperative cardiac outcomes.
    • Elderly patients with cardiovascular risk factors face even higher perioperative risks.
    • Prophylaxis is challenged by heterogeneity of aging, unpredictable interactions, and diagnostic difficulties.