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Related Experiment Videos

Awake intubation made easy and acceptable.

S A Jenkins1, C F Marshall

  • 1Department of Anaesthesia, Queen Elizabeth Hospital, Woodville, South Australia.

Anaesthesia and Intensive Care
|November 30, 2000
PubMed
Summary
This summary is machine-generated.

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A novel aerosolized lignocaine technique for nasal, pharyngeal, and laryngeal administration improved endotracheal intubation conditions. This method was well-tolerated, safe, and effective in unsedated volunteers.

Area of Science:

  • Anesthesiology
  • Pharmacology

Background:

  • Effective topical anesthesia is crucial for airway procedures like endotracheal intubation.
  • Traditional methods may have limitations in efficacy or patient tolerance.

Purpose of the Study:

  • To evaluate the efficacy and safety of aerosolized lignocaine administered via a simple device for endotracheal intubation in unsedated volunteers.

Main Methods:

  • A custom device using an Optiva cannula and oxygen supply delivered aerosolized lignocaine to the nose, pharynx, and larynx.
  • Ten unsedated, unpremedicated volunteers underwent intubation following lignocaine administration.
  • Plasma lignocaine concentrations and hemodynamic stability were monitored.

Main Results:

  • Mean intubation time was 12 minutes (range 8-19 minutes) after lignocaine administration.

Related Experiment Videos

  • Intubating conditions were rated as good and the procedure was well-tolerated by all subjects.
  • Mean lignocaine dose was 4.8 mg/kg, with plasma concentrations below toxic levels and stable hemodynamics without desaturation.

    • Conclusions:

    • Aerosolized lignocaine delivered via a simple device provides effective topical anesthesia for endotracheal intubation.
    • This technique offers a safe and well-tolerated alternative for airway management in awake patients.