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Low-dose "renal" dopamine
1Department of Anesthesia, Cleveland Clinic Foundation, Ohio, USA. oharaj@ccf.org
Anesthesiology Clinics of North America
|November 30, 2000
Summary
Low-dose renal dopamine is used for patients with or at risk of kidney dysfunction. This review covers its history, evidence, and clinical uses in acute renal failure.
Area of Science:
- Nephrology
- Pharmacology
Background:
- Acute renal failure (ARF) poses significant risks to patients.
- Low-dose dopamine is a therapeutic option for renal dysfunction.
Purpose of the Study:
- To review the impact of ARF on patients.
- To discuss the history and use of dopamine therapy in renal dysfunction.
- To analyze the evidence, side effects, and indications for low-dose renal dopamine.
Main Methods:
- Literature review of acute renal failure.
- Review of dopamine therapy in renal dysfunction.
- Analysis of clinical evidence and side effects.
Main Results:
- Low-dose renal dopamine is administered to patients at risk for or with established ARF.
- Evidence for its efficacy is mixed, with some positive and some equivocal findings.
- Potential side effects and clinical indications are discussed.
Conclusions:
- Low-dose renal dopamine remains a therapy option for specific patient populations with renal dysfunction.
- Further research may clarify its optimal use and efficacy in ARF.