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Low-dose "renal" dopamine.

J F O'Hara1

  • 1Department of Anesthesia, Cleveland Clinic Foundation, Ohio, USA. oharaj@ccf.org

Anesthesiology Clinics of North America
|November 30, 2000
PubMed
Summary
This summary is machine-generated.

Low-dose renal dopamine is used for patients with or at risk of kidney dysfunction. This review covers its history, evidence, and clinical uses in acute renal failure.

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Area of Science:

  • Nephrology
  • Pharmacology

Background:

  • Acute renal failure (ARF) poses significant risks to patients.
  • Low-dose dopamine is a therapeutic option for renal dysfunction.

Purpose of the Study:

  • To review the impact of ARF on patients.
  • To discuss the history and use of dopamine therapy in renal dysfunction.
  • To analyze the evidence, side effects, and indications for low-dose renal dopamine.

Main Methods:

  • Literature review of acute renal failure.
  • Review of dopamine therapy in renal dysfunction.
  • Analysis of clinical evidence and side effects.

Main Results:

  • Low-dose renal dopamine is administered to patients at risk for or with established ARF.

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  • Evidence for its efficacy is mixed, with some positive and some equivocal findings.
  • Potential side effects and clinical indications are discussed.
  • Conclusions:

    • Low-dose renal dopamine remains a therapy option for specific patient populations with renal dysfunction.
    • Further research may clarify its optimal use and efficacy in ARF.