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Related Experiment Videos

The repeatability of corneal thickness measures.

M W Marsich1, M A Bullimore

  • 1The Ohio State University, College of Optometry, Columbus 43210, USA.

Cornea
|November 30, 2000
PubMed
Summary

The Orbscan system offers the most repeatable corneal thickness measurements compared to ultrasound and optical pachymetry. However, it tends to overestimate corneal thickness.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optometry

Background:

  • Accurate measurement of corneal thickness is crucial for diagnosing and managing various ocular conditions.
  • Repeatability of measurement techniques directly impacts clinical decision-making and patient outcomes.

Purpose of the Study:

  • To compare the day-to-day and same-day repeatability of three central corneal thickness measurement devices: Orbscan Slitscan pachymetry, ultrasound pachymetry, and optical pachymetry.
  • To assess the limits of agreement for each pachymetry method.

Main Methods:

  • Twenty healthy subjects underwent three separate corneal thickness measurements of their right eye.
  • Measurements were performed using a Haag-Streit optical pachymeter, a Humphrey Model 855 ultrasound pachymeter, and the Orbscan system.
  • Repeatability was analyzed using Bland-Altman plots to determine mean difference and 95% limits of agreement.

Main Results:

  • The Orbscan system demonstrated the highest repeatability for central corneal thickness measurements, with 95% limits of agreement of -10 to +17 micrometers.
  • Ultrasound pachymetry showed moderate repeatability (-22 to +24 micrometers), while optical pachymetry exhibited the poorest repeatability (-61 to +32 micrometers).
  • The Orbscan system consistently yielded higher corneal thickness values compared to both ultrasound and optical methods.

Conclusions:

  • The Orbscan system is the most repeatable device for measuring central corneal thickness.
  • Clinicians should be aware of the Orbscan's tendency to overestimate corneal thickness, necessitating careful interpretation of results in conjunction with other pachymetry methods.

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