Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-specificity identification of large vessel occlusion stroke using D-dimer and NT-proBNP combined with clinical variables.

Frontiers in neurology·2026
Same author

Impact of SARS-CoV-2 infection on perioperative mortality.

Revista clinica espanola·2025
Same author

Discovery and insights from DSX mission's high-power VLF wave transmission experiments in the radiation belts.

Scientific reports·2022
Same author

A Review of the EUSO-Balloon Pathfinder for the JEM-EUSO Program.

Space science reviews·2022
Same author

Influence of surface morphology and internal structure on the mechanical properties and tribological response of Boa Red Tail and Python Regius snake skin.

Journal of the mechanical behavior of biomedical materials·2021
Same author

SEOM clinical guideline thyroid cancer (2019).

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2020

Related Experiment Video

Updated: Jul 15, 2026

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
09:13

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve

Published on: June 14, 2017

Proteomics: new perspectives, new biomedical opportunities.

R E Banks1, M J Dunn, D F Hochstrasser

  • 1ICRF Cancer Medicine Research Unit, St James's University Hospital, Leeds, UK. r.banks@leeds.ac.uk

Lancet (London, England)
|November 30, 2000
PubMed
Summary

Proteomics offers a deeper understanding of biological functions beyond genomics by analyzing expressed proteins. This technology aids in biomedical research, from understanding disease to developing new drugs and vaccines.

More Related Videos

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools
07:01

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools

Published on: August 19, 2025

Related Experiment Videos

Last Updated: Jul 15, 2026

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
09:13

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve

Published on: June 14, 2017

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools
07:01

Navigating the Mass Spectrometry-Based Proteomic Data Using Free Computational Tools

Published on: August 19, 2025

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Proteomics

Background:

  • Genomic data alone is insufficient to understand protein expression and function.
  • Post-translational modifications significantly impact protein activity.
  • Environmental factors and complex diseases require analysis beyond the genome.

Purpose of the Study:

  • To review the technology behind proteomics-based approaches.
  • To illustrate the biomedical applications of proteomics.
  • To explore potential clinical uses of proteomics.

Main Methods:

  • Proteomics-based approaches analyzing expressed proteins.
  • Examination of post-translational modifications (e.g., phosphorylation, glycosylation).
  • Integration of genomic and proteomic data.

Main Results:

  • Proteomics complements genomics by revealing protein quantity and modifications.
  • Demonstrated utility in understanding disease pathogenesis, such as neurological disorders.
  • Identified applications in drug discovery and vaccine development.

Conclusions:

  • Proteomics is crucial for a comprehensive understanding of biological systems.
  • The technology holds significant promise for clinical applications in medicine.
  • Further exploration of proteomics will advance biomedical research and patient care.