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Ventricular thrombosis in Sipple's syndrome
1Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Iran.
Southern Medical Journal
|November 30, 2000
Abstract:
An 18-year-old girl with multiple endocrine neoplasia type 2 (Sipple's syndrome) had a large intraventricular mass that proved to be a thrombus. She had no apparent precipitating factor for intracavitary thrombus formation. This is the first reported case of multiple endocrine neoplasia associated with ventricular thrombus. A hypercoagulable state resulting from catecholamine-induced and serotonin-induced platelet hyperaggregability might have been the causative mechanism.