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Published on: December 8, 2011
Candiduria: When and How to Treat It
1Department of Medicine, Medical College of Georgia, 1120 Fifteenth Street, CB 1831, Augusta, GA 30912, USA. jfisher@mail.mcg.edu
Current Infectious Disease Reports
|November 30, 2000
Summary
Candiduria, or yeast in urine, requires careful evaluation. Asymptomatic cases often don't need antifungal treatment; focus on predisposing factors. Treatment options exist for severe infections.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Clinical Urology
Background:
- Candiduria presents a diagnostic challenge, ranging from contamination to severe fungal infections.
- Distinguishing true infection from contamination is crucial for appropriate patient management.
- Understanding patient status and clinical context is key to evaluating candiduria.
Purpose of the Study:
- To review the significance and evaluation of candiduria.
- To outline management strategies for asymptomatic and symptomatic candiduria.
- To discuss the role of various antifungal agents in treating urinary tract fungal infections.
Main Methods:
- Literature review of clinical findings and management of candiduria.
- Analysis of diagnostic validation and patient assessment protocols.
- Evaluation of antifungal treatment options, including amphotericin B, azoles, and flucytosine.
Main Results:
- Asymptomatic candiduria in stable patients typically does not require antifungal therapy.
- Management should prioritize addressing predisposing factors when feasible.
- Parenteral amphotericin B is indicated for severe, widespread infections or resistant Candida.
- Fluconazole is a primary choice for susceptible strains, though optimal dosing is not established.
- Intravesical amphotericin B is more valuable diagnostically than therapeutically.
Conclusions:
- Proper evaluation of candiduria involves validating funguria, considering the clinical setting, and assessing patient status.
- Treatment decisions for candiduria should be individualized based on clinical presentation and pathogen susceptibility.
- Antifungal agents like amphotericin B, fluconazole, and flucytosine have specific roles in managing urinary tract candidiasis.
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