Adipose redistribution in human immunodeficiency virus-seropositive patients: association with CD4 response

We have noted that human immunodeficiency virus (HIV)-seropositive patients who develop adipose redistribution (AR) while receiving combination antiretroviral therapy (ART) also tend to have a better response to ART, as indicated by the relative change in CD4 percent compared to those who don't develop AR on therapy. Whether the possible benefits of the improved CD4 response outweigh the metabolic and cosmetic problems associated with lipodystrophy is not known.