Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vancomycin Use in a Brazilian University Hospital: Comparison With Hospital Infection Control Practices Advisory

Couto1, Leles, Lima

  • 1Department of Pathology, Infection Control Committee, Uberlândia Federal University, Brazil.

The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases
|November 30, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Determination of SO(2) in Wines Using a Flow Injection Analysis System with Potentiometric Detection.

Journal of agricultural and food chemistry·2001
Same author

On-off intermittency at the onset of the ion-acoustic instability in a laboratory plasma

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics·2000
Same author

Differential expression of the two cytosolic glutamine synthetase genes in various organs of Medicago truncatula.

Plant science : an international journal of experimental plant biology·2000
Same author

Observation of the 11N ground state

Physical review letters·2000
Same author

Relationship between dental morphology, sex, body length and age in Pontoporia blainvillei and Sotalia fluviatilis (Cetacea) in Northern Rio de Janeiro, Brazil.

Revista brasileira de biologia·2000
Same author

[Sand flies in Timóteo, Minas Gerais, Brazil]

Cadernos de saude publica·2000

Vancomycin prescribing at a Brazilian hospital often did not follow guidelines, leading to resistance concerns. Improved education and infectious disease specialist review are needed for appropriate vancomycin use.

Area of Science:

  • Infectious Diseases
  • Hospital Pharmacy
  • Antimicrobial Stewardship

Background:

  • Emergence of vancomycin-resistant bacteria poses a significant public health threat.
  • Hospital Infections Control Practices Advisory Committee (HICPAC) guidelines aim to optimize vancomycin prescribing.
  • Evaluating adherence to these guidelines is crucial for antimicrobial stewardship.

Purpose of the Study:

  • To assess vancomycin utilization patterns at Uberlândia University Hospital in Brazil.
  • To determine the extent of adherence to HICPAC guidelines for vancomycin prescribing.
  • To identify factors associated with non-adherence and the emergence of resistant strains.

Main Methods:

  • A prospective study involving 31 patients receiving vancomycin over 10 months.

Related Experiment Videos

  • Nasal and rectal cultures were performed to monitor for Vancomycin-Resistant Enterococci (VRE) and Methicillin-Resistant Staphylococcus aureus (MRSA).
  • Patient records were reviewed to collect demographic and clinical data, and assess HICPAC guideline adherence.

    • Main Results:

    • 68% of vancomycin use (21/31 patients) did not adhere to HICPAC guidelines, primarily due to empirical prescribing without documented need.
    • Non-adherence was higher when vancomycin was used without Infectious Diseases (ID) specialist approval (81%) compared to with approval (53%).
    • Despite non-adherence, empirical vancomycin use approved by ID specialists in severely ill patients (75%) may have been appropriate, though outside guidelines.

    Conclusions:

    • Significant non-adherence to HICPAC vancomycin prescribing guidelines was observed.
    • There is a critical need for enhanced education on appropriate vancomycin use.
    • Increased review by ID specialists, particularly on medicine services, is recommended to improve vancomycin stewardship.