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Sudden Electrical Death.

Lerman1, Cannom

  • 1Good Samaritan Hospital, Department of Cardiology, 1225 Wilshire Boulevard, Los Angeles, CA 90017, USA.

Current Treatment Options in Cardiovascular Medicine
|November 30, 2000
PubMed
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Survivors of ventricular fibrillation or tachycardia should generally receive an implantable cardioverter defibrillator (ICD) for improved survival. Treating the underlying cause of the heart rhythm is also crucial.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Out-of-hospital ventricular fibrillation and sustained ventricular tachycardia are life-threatening arrhythmias.
  • Identifying and treating the underlying cardiomyopathy is essential for managing these patients.

Purpose of the Study:

  • To evaluate the efficacy of implantable cardioverter defibrillators (ICDs) compared to antiarrhythmic drug therapy in survivors of ventricular arrhythmias.
  • To emphasize the importance of addressing underlying causes of ventricular rhythm disturbances.

Main Methods:

  • Review of recently published clinical trials comparing ICDs with antiarrhythmic drugs.
  • Discussion of the role of pharmacologic therapy (ACE inhibitors, beta-blockers, aspirin) and electrophysiologic studies.

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Main Results:

  • Clinical trials indicate improved survival rates with ICD implantation in eligible patients.
  • Optimal medical management of underlying cardiomyopathies is a key component of care.

Conclusions:

  • Implantable cardioverter defibrillators (ICDs) are recommended over antiarrhythmic drugs for most survivors of non-reversible ventricular fibrillation or significant ventricular tachycardia.
  • Comprehensive management includes addressing the underlying cardiac condition and considering device therapy.