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Increased arterial wave reflection may predispose syncopal attacks.

C H Chen1, H H Hu, Y P Lin

  • 1Department of Medicine and Center of Neuroscience, Taipei Veterans General Hospital, Taiwan.

Clinical Cardiology
|November 30, 2000
PubMed
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Increased arterial wave reflection is linked to syncope, particularly in older adults. This study found higher augmentation index in syncope patients, suggesting a predisposition.

Area of Science:

  • Cardiology
  • Geriatrics
  • Vascular Physiology

Background:

  • Syncope incidence rises with age.
  • Aging correlates with heightened arterial wave reflection.

Purpose of the Study:

  • To investigate if increased arterial wave reflection predisposes individuals to syncope.
  • To explore the association between arterial hemodynamics and syncope events.

Main Methods:

  • Recruited 38 syncope patients and 54 controls.
  • Assessed vasomotor function, cerebral flow, and cardiac function.
  • Measured carotid augmentation index (AI) noninvasively.

Main Results:

  • Syncope patients exhibited a significantly greater AI compared to controls (20% vs. 10%, p=0.013).

Related Experiment Videos

  • In patients over 50, AI was markedly higher (29% vs. 11%, p<0.001).
  • Enhanced wave reflection persisted after adjusting for cardiovascular risk factors.

    • Conclusions:

    • Findings support that enhanced arterial wave reflection is associated with syncope.
    • This association is particularly pronounced in the elderly population.