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Current Australian practice in the prevention and management of corneal allograft rejection
N H Barker1, T R Henderson, C A Ross
1Department of Ophthalmology, Flinders University of South Australia, Bedford Park, Australia.
Purpose:
To determine current practices in the prevention and management of corneal allograft rejection in Australia.
Methods:
A questionnaire was circulated to attendees at the 1998 Eye Bank Meeting in Adelaide. Twenty-four responses were received and analysed.
Results:
All respondents used topical corticosteroids for routine prophylaxis and to treat established rejection episodes. Prednisolone acetate was the most frequently prescribed topical corticosteroid. Systemic non-steroidal immunosuppression was prescribed almost exclusively for high-risk grafts. Seventy-five per cent of surgeons used systemic antiviral agents for the treatment of graft rejection in patients with Herpes simplex keratitis.
Conclusion:
There was a wide variation amongst surgeons in the choice of therapy for routine prophylactic immunosuppression as well as for the treatment of established corneal allograft rejection.