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[Macular changes due to corticosteroids (author's transl)].

H Pau

    Klinische Monatsblatter Fur Augenheilkunde
    |April 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

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    High corticosteroid doses in a child caused Cushing's syndrome and osteoporosis. Ocular complications included pigmental fissures in the macula, affecting vision.

    Area of Science:

    • Ophthalmology
    • Endocrinology
    • Pediatrics

    Background:

    • Corticosteroids are potent anti-inflammatory drugs with significant side effects.
    • Prolonged high-dose corticosteroid use can lead to iatrogenic Cushing's syndrome.

    Observation:

    • A nine-year-old girl presented with symptoms of Cushing's syndrome after five years of high-dose corticosteroid therapy.
    • The patient developed osteoporosis, a known complication of long-term corticosteroid use.

    Findings:

    • Striate and circular pigmental fissures were observed in the macula of both eyes.
    • These fissures extended to the optic disc (papilla), indicating potential visual pathway involvement.

    Implications:

    • This case highlights the potential for severe ocular complications, including macular pigmental changes, secondary to corticosteroid-induced Cushing's syndrome in children.

    Related Experiment Videos

  • Ophthalmological monitoring is crucial in pediatric patients undergoing long-term high-dose corticosteroid treatment.