Letter: Single-strand breaks in DNA--treated with MNNG

Use of monoacetyl-4-hydroxyaminoquinoline 1-oxide to probe contacts between guanines and protein in the minor and major grooves of DNA. Interaction of Escherichia coli integration host factor with its recognition site in the early promoter and transposition enhancer of bacteriophage Mu.

Biochemistry·1991

The reaction of acetyl-4-hydroxyaminoquinoline 1-oxide with DNA: quantitation of single-strand break formation and hyper-reactivity of DNA termini.

Carcinogenesis·1991

Sequence effect on incision by (A)BC excinuclease of 4NQO adducts and UV photoproducts.

Nucleic acids research·1991

The N2-guanine adduct but not the C8-guanine or N6-adenine adducts formed by 4-nitroquinoline 1-oxide blocks the 3'-5' exonuclease action of T4 DNA polymerase.

Biochemistry·1990

Low levels of DNA excision repair in undamaged bovine lymphocytes.

Mutation research·1988

Lack of excision of 4HAQO adducts from DNA by cell extracts that excise pyrimidine dimers.

Biochemical and biophysical research communications·1986

Transcriptomic Profiling of Mouse Mammary Tumors Enables Prognostic and Predictive Biomarker Discovery for Human Breast Cancer.

Cancer research·2026

RASA2 Promotes Pancreatic Cancer Metastasis by Activating TGFβ-Dependent Non-canonical Hedgehog Signaling.

Cancer research·2026

KRASG12V Degraders Provide a Potential Therapeutic Opportunity in Lung Adenocarcinoma.

Cancer research·2026

Aberrant O-glycosylation Induces IL-34-Mediated Immune Remodeling and Promotes Pancreatic Cancer Progression.

Cancer research·2026

Fasting-Mimicking Diets Reprogram Cancer-Associated Fibroblasts to Reverse the Immunosuppressive Tumor Microenvironment in Breast Cancer.

Cancer research·2026

Spatial Profiling Reveals Immune Escape Pathways and Therapeutic Vulnerabilities in Prostate Cancer Bone Metastases.

Cancer research·2026

Medical research and health care finance: Evidence from Academic Medical Centers.

Research policy·2026

Risk Factors for Peritonitis Associated With Endoscopic Ultrasound-guided Hepaticogastrostomy.

DEN open·2026

Demystifying Computational Biology: A Scalable Drug Discovery Framework for Medical Curricula.

Cureus·2026

Advances in antibiofilm strategies for medical implant-associated infections: emerging technologies and translational challenges.

Frontiers in microbiology·2026

Recent advances in ultrasound microbubble-mediated gold-based nanomaterials for cancer theranostics.

Frontiers in chemistry·2026

Reversing Antibiotic Resistance and Reprogramming Macrophage Polarization by Extracellular Vesicles from Fresh Schisandra chinensis: A Dual Pharmacological Strategy for Drug-Resistant Wound Infection and Sepsis.

Pharmacological research·2026

Related Experiment Videos

Letter: Single-strand breaks in DNA--treated with MNNG

Related Concept Videos

Use of monoacetyl-4-hydroxyaminoquinoline 1-oxide to probe contacts between guanines and protein in the minor and major grooves of DNA. Interaction of Escherichia coli integration host factor with its recognition site in the early promoter and transposition enhancer of bacteriophage Mu.

The reaction of acetyl-4-hydroxyaminoquinoline 1-oxide with DNA: quantitation of single-strand break formation and hyper-reactivity of DNA termini.

Sequence effect on incision by (A)BC excinuclease of 4NQO adducts and UV photoproducts.

The N2-guanine adduct but not the C8-guanine or N6-adenine adducts formed by 4-nitroquinoline 1-oxide blocks the 3'-5' exonuclease action of T4 DNA polymerase.

Low levels of DNA excision repair in undamaged bovine lymphocytes.

Lack of excision of 4HAQO adducts from DNA by cell extracts that excise pyrimidine dimers.

Transcriptomic Profiling of Mouse Mammary Tumors Enables Prognostic and Predictive Biomarker Discovery for Human Breast Cancer.

RASA2 Promotes Pancreatic Cancer Metastasis by Activating TGFβ-Dependent Non-canonical Hedgehog Signaling.

KRASG12V Degraders Provide a Potential Therapeutic Opportunity in Lung Adenocarcinoma.

Aberrant O-glycosylation Induces IL-34-Mediated Immune Remodeling and Promotes Pancreatic Cancer Progression.

Fasting-Mimicking Diets Reprogram Cancer-Associated Fibroblasts to Reverse the Immunosuppressive Tumor Microenvironment in Breast Cancer.

Spatial Profiling Reveals Immune Escape Pathways and Therapeutic Vulnerabilities in Prostate Cancer Bone Metastases.

Medical research and health care finance: Evidence from Academic Medical Centers.

Risk Factors for Peritonitis Associated With Endoscopic Ultrasound-guided Hepaticogastrostomy.

Demystifying Computational Biology: A Scalable Drug Discovery Framework for Medical Curricula.

Advances in antibiofilm strategies for medical implant-associated infections: emerging technologies and translational challenges.

Recent advances in ultrasound microbubble-mediated gold-based nanomaterials for cancer theranostics.

Reversing Antibiotic Resistance and Reprogramming Macrophage Polarization by Extracellular Vesicles from Fresh Schisandra chinensis: A Dual Pharmacological Strategy for Drug-Resistant Wound Infection and Sepsis.

Related Experiment Videos

Letter: Single-strand breaks in DNA--treated with MNNG

Related Concept Videos

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