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[Contagious impetigo--pathogen spectrum and therapeutic consequences].
1Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technischen Universität München. D.Abeck@lrz.tu-muenchen.de
Deutsche Medizinische Wochenschrift (1946)
|December 1, 2000
Summary
Staphylococcus aureus is the primary cause of contagious impetigo (C.I.). Flucloxacillin and cefotaxime are effective treatments, but macrolides are not recommended due to resistance.
Area of Science:
- Dermatology
- Microbiology
- Infectious Diseases
Context:
- Contagious impetigo (C.I.) is a common bacterial skin infection, particularly in children.
- Understanding the causative pathogens and their antibiotic susceptibility is crucial for effective treatment.
Purpose:
- To compare the clinical presentation of C.I. with its causative organisms.
- To determine bacterial susceptibility patterns to guide appropriate C.I. therapy.
Summary:
- Staphylococcus aureus was the predominant pathogen identified in 126 C.I. patients.
- High resistance rates (>20%) were observed for erythromycin.
- Staphylococcal isolates showed high sensitivity to flucloxacillin and cefotaxime, with low resistance to fusidic acid and mupirocin.
Impact:
- S. aureus is the leading cause of C.I. and should be the primary consideration for treatment.
- Penicillinase-stable penicillins or cephalosporins are recommended for oral C.I. therapy.
- Macrolides are no longer advised for initial C.I. treatment due to resistance.