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Related Experiment Videos

[Contagious impetigo--pathogen spectrum and therapeutic consequences].

D Abeck1, M Mempel, H P Seidl

  • 1Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technischen Universität München. D.Abeck@lrz.tu-muenchen.de

Deutsche Medizinische Wochenschrift (1946)
|December 1, 2000
PubMed
Summary

Staphylococcus aureus is the primary cause of contagious impetigo (C.I.). Flucloxacillin and cefotaxime are effective treatments, but macrolides are not recommended due to resistance.

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Topical hydrocortisone 17-butyrate 21-propionate in the treatment of inflammatory skin diseases: pharmacological data, clinical efficacy, safety and calculation of the therapeutic index.

Die Pharmazie·2016

Area of Science:

  • Dermatology
  • Microbiology
  • Infectious Diseases

Context:

  • Contagious impetigo (C.I.) is a common bacterial skin infection, particularly in children.
  • Understanding the causative pathogens and their antibiotic susceptibility is crucial for effective treatment.

Purpose:

  • To compare the clinical presentation of C.I. with its causative organisms.
  • To determine bacterial susceptibility patterns to guide appropriate C.I. therapy.

Summary:

  • Staphylococcus aureus was the predominant pathogen identified in 126 C.I. patients.
  • High resistance rates (>20%) were observed for erythromycin.
  • Staphylococcal isolates showed high sensitivity to flucloxacillin and cefotaxime, with low resistance to fusidic acid and mupirocin.

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Impact:

  • S. aureus is the leading cause of C.I. and should be the primary consideration for treatment.
  • Penicillinase-stable penicillins or cephalosporins are recommended for oral C.I. therapy.
  • Macrolides are no longer advised for initial C.I. treatment due to resistance.