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[Melanoma. Results with "sentinel node" sampling].

H K Büchels¹, H Vogt, H Starz

¹Plastische Chirurgie, Klinik für Allgemein- und Viszeralchirurgie, Zentralklinikum Augsburg.

Zentralblatt Fur Chirurgie

|December 1, 2000

Summary

This summary is machine-generated.

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Gamma probe-guided sentinel lymph node evaluation (SLNE) successfully detected and removed lymph nodes in 99.3% of melanoma patients. This technique identified micrometastases in over half of advanced melanoma cases, aiding in accurate staging.

Area of Science:

Oncology
Surgical Oncology
Nuclear Medicine

Context:

Sentinel lymphadenectomy (SLNE) is a crucial staging procedure for melanoma.
Accurate detection of lymph node metastasis is vital for treatment planning.

Purpose:

To evaluate the efficacy of gamma probe-guided sentinel lymph node evaluation (SLNE) in melanoma patients.
To assess the detection rate of micrometastases and subsequent metastases in lymph node dissections.

Summary:

Gamma probe-guided SLNE was performed on 274 melanoma patients using 99mTc-labeled colloid.
The technique achieved a 99.3% success rate for SLN detection and excision.
Micrometastases were found in 53.1% of pT3/pT4 melanomas, with 30% of radical dissections revealing additional metastases.

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Regional recurrence was observed in only one SLN-negative patient.

Impact:

SLNE significantly improves the accuracy of melanoma staging.
Early detection of micrometastases via SLNE can guide adjuvant therapy decisions.
Minimally invasive SLNE reduces the morbidity associated with complete lymph node dissection.