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BBID: the biological biochemical image database.

K G Becker1, S L White, J Muller

  • 1DNA Array Unit, RRB NCTS, National Institutes on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA. beckerk@grc.nia.nih.gov

Bioinformatics (Oxford, England)
|December 1, 2000
PubMed
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The Biological Biochemical Image Database archives images of eukaryotic regulatory pathways. This resource aids in efficiently studying complex gene expression and testing biological pathways.

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Bioinformatics

Background:

  • Research articles on higher eukaryotic regulatory pathways generate numerous images.
  • Archived images are often difficult to access and query for pathway analysis.
  • Understanding complex gene expression requires efficient tools for pathway investigation.

Purpose of the Study:

  • To create a WWW-accessible relational database of archived images from research articles.
  • To annotate pathway information for querying.
  • To facilitate the empirical testing of complex regulatory pathways.

Main Methods:

  • Development of a WWW-accessible relational database.
  • Archiving and annotating images from research articles.
  • Implementing query functionalities for pathway information.

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Main Results:

  • The Biological Biochemical Image Database provides accessible archived images.
  • Pathway information is annotated and searchable.
  • The database supports the study of complex gene expression.

Conclusions:

  • The Biological Biochemical Image Database enables efficient empirical testing of complex regulatory pathways.
  • This resource is valuable for large-scale gene-expression systems analysis.
  • Facilitates research in higher eukaryotic regulatory networks.