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Benign pneumatosis in children
1Department of Radiology, Children's Hospital, Boston, MA 02115, USA. fenton.laura@tchden.org
Insights
Pneumatosis intestinalis (PI) in children, often benign, typically occurs with underlying risk factors, especially immunosuppression. Most cases resolve with conservative management, but clinical decline may necessitate surgery.
Area of Science:
- Pediatric Gastroenterology
- Medical Imaging
Background:
- Pneumatosis intestinalis (PI) is commonly linked to necrotizing enterocolitis in premature infants.
- Beyond infancy, PI is rare, with "benign pneumatosis" characterized by mild symptoms and resolution through conservative treatment.
Purpose of the Study:
- To characterize benign PI in pediatric patients.
- Identify associated risk factors, presenting symptoms, management strategies, and patient outcomes.
Main Methods:
- Retrospective review of medical records and radiographs for children diagnosed with PI between 1990 and 1998.
- Analysis of underlying conditions, clinical presentation, treatment approaches, and outcomes.
Main Results:
- Thirty-seven children (mean age 4 years) were included in the study.
- Thirty-two children had identifiable risk factors, with 25 being immunocompromised.
- Conservative management led to PI resolution in 35 children; two required surgery, and one patient died.
Conclusions:
- Benign PI occurs in children, frequently associated with underlying risk factors, particularly immunosuppression.
- Clinical deterioration is a key indicator for surgical intervention.
- The majority of pediatric PI cases resolve with conservative management.
Background:
In pediatrics, pneumatosis intestinalis (PI) is usually due to necrotizing enterocolitis in premature newborns. Beyond infancy, PI is uncommon. "Benign pneumatosis" is PI in patients with few or no symptoms that resolves with conservative management.
Objective:
Our goal was to better characterize benign PI in children. Our investigation focused on identifying underlying risk factors, symptoms at time of diagnosis, management and outcome.
Materials And Methods:
Available medical records and radiographs of children with pneumatosis intestinalis from 1990 to 1998 were reviewed for underlying conditions, symptoms at time of radiographs, management and outcome.
Results:
Thirty-seven children (mean age 4 years) were included. Thirty-two children had identifiable risk factors. Twenty-five children were immunocompromised by their underlying conditions or therapeutic regimen. Thirty-five children were managed conservatively with resolution of PI. Two patients, however, required surgery and one patient died.
Conclusion:
Benign pneumatosis does occur in children. The majority have underlying risk factors, most commonly related to immunosuppression. Clinical deterioration is the most useful indicator for surgical intervention. In most patients PI resolves with conservative management.
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