Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Best's vitelliform macular dystrophy.

W E Benson, A E Kolker, J M Enoch

    American Journal of Ophthalmology
    |January 11, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Topical timolol administration reduces the incidence of glaucomatous damage in ocular hypertensive individuals. A randomized, double-masked, long-term clinical trial (1).

    Journal of glaucoma·2009
    Same author

    Diagnosis and treatment of cyclodialysis clefts.

    Journal of glaucoma·2009
    Same author

    Long-term progression at individual mean intraocular pressure levels in primary open-angle and exfoliative glaucoma.

    European journal of ophthalmology·2008
    Same author

    Patient-initiated second medical opinions: their necessity and economic cost.

    Retina (Philadelphia, Pa.)·2002
    Same author

    The enigma of early lens use.

    Technology and culture·2001
    Same author

    Surgical management of macular holes: a report by the American Academy of Ophthalmology.

    Ophthalmology·2001
    Same journal

    Therapeutic Advances in Corneal Scar management: Topical Treatments, Mesenchymal Cell Therapy and Stromal Transplantation.

    American journal of ophthalmology·2026
    Same journal

    Increased Risk for Ocular Surface Neoplasia in Recipients of Solid Organ Transplant.

    American journal of ophthalmology·2026
    Same journal

    Aflibercept With vs Without Reduced-Fluence Photodynamic Therapy for Polypoidal Choroidal Vasculopathy: Optical Coherence Tomography Angiographic changes from a randomized clinical trial.

    American journal of ophthalmology·2026
    Same journal

    Posterior Segment Risk Factors for Penetrating Keratoplasty Failure.

    American journal of ophthalmology·2026
    Same journal

    Rates, Timing, and Predictors of Retreatment Across Risk-Cohorts in Retinopathy of Prematurity: Intravitreal Bevacizumab Injection vs Laser.

    American journal of ophthalmology·2026
    Same journal

    Second-Generation ELZA-sub400 Protocol: Individualized High-Fluence Cross-Linking for Ultra-Thin Keratoconus Corneas.

    American journal of ophthalmology·2026
    See all related articles

    Best's vitelliform macular dystrophy can preserve visual function despite foveal changes. Trauma-induced rupture led to vision loss and abnormal receptor alignment, highlighting disease progression factors.

    Area of Science:

    • Ophthalmology
    • Retinal Diseases
    • Macular Dystrophy

    Background:

    • Best's vitelliform macular dystrophy (BVMD) is an inherited retinal disorder affecting central vision.
    • Understanding the structural and functional consequences of BVMD is crucial for patient management.

    Observation:

    • A patient with BVMD presented with an intact vitelliform disk in the right eye, showing minimal visual acuity and receptor alignment impact.
    • The left eye's vitelliform disk ruptured due to blunt trauma, leading to subretinal macular neovascularization.

    Findings:

    • Despite foveal elevation, the right eye maintained good visual acuity, hue discrimination, and normal electroretinogram/visually evoked response, indicating preserved receptor alignment mechanisms.
    • The left eye experienced reduced visual acuity, decreased retinal sensitivity, and abnormal receptor orientation post-rupture and neovascularization.

    Related Experiment Videos

    Implications:

    • Suggests that intact vitelliform lesions may preserve visual function longer in BVMD.
    • Highlights the detrimental effect of trauma and subsequent neovascularization on visual integrity in BVMD patients.
    • Emphasizes the importance of receptor alignment for maintaining visual acuity in macular dystrophies.