Hypoglycemic sensorimotor polyneuropathy associated with insulinoma
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Updated: Oct 10, 2026

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
Published on: May 10, 2018
J G Heckmann1, W Dietrich, W Hohenberger
1Department of Neurology, University Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen, Germany. josef.heckmann@neuro.med.uni-erlangen.de
Abstract:
Hypoglycemia-induced peripheral neuropathy due to insulinoma is unusual and, as far as we know, has previously been reported in only 34 patients. In this case report, we describe the clinical features, electrophysiological features, and pathological findings in a 37-year-old patient with polyneuropathy from repeated hypoglycemic episodes over a 9-year period that related to an insulinoma. The literature is discussed. The reported case is of special interest because the peripheral neuropathy led to the correct diagnosis.
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