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Related Experiment Videos

Secretion from human apocrine glands: an electron microscopic study.

G Schaumburg-Lever, W F Lever

    The Journal of Investigative Dermatology
    |January 1, 1975
    PubMed
    Summary

    Electron microscopy revealed three apocrine gland secretion types: merocrine, apocrine, and holocrine. Each method involves distinct cellular processes for releasing secretory products into the gland lumen.

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    Area of Science:

    • Cell Biology
    • Histology
    • Glandular Secretion

    Background:

    • Apocrine glands are specialized structures involved in secretion.
    • Understanding the mechanisms of apocrine gland secretion is crucial for cell biology.

    Purpose of the Study:

    • To investigate and classify the different modes of secretion in apocrine glands using electron microscopy.
    • To provide a detailed ultrastructural description of merocrine, apocrine, and holocrine secretion.

    Main Methods:

    • Utilized electron microscopy for high-resolution imaging of apocrine gland ultrastructure.
    • Observed and documented the dynamic processes of secretory product release.

    Main Results:

    • Identified and characterized three distinct secretion types: merocrine, apocrine, and holocrine.
    • Merocrine secretion involves vesicular release from the Golgi.
    • Apocrine secretion proceeds through apical cap formation, membrane division, and tubule-mediated separation.
    • Holocrine secretion involves the disintegration of entire secretory cells or cell strands.

    Conclusions:

    • Apocrine glands exhibit diverse secretory mechanisms.
    • The observed secretion types (merocrine, apocrine, holocrine) represent distinct pathways for cellular product release.

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