Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Whither genomics?

A W Murray1

  • 1Department of Physiology, University of California San Francisco, CA 94143, USA. amurray@mcb.harvard.edu.

Genome Biology
|December 6, 2000
PubMed
Summary
This summary is machine-generated.

Genome-wide analysis generates vast biological data. New interdisciplinary methods are essential to transform this data into pathway information, advancing our understanding of life's functions and evolution.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maximising the impact of your work using infographics.

Bone & joint research·2017
Same author

Quantification of radiation exposure in the operating theatre during management of common fractures of the upper extremity in children.

Annals of the Royal College of Surgeons of England·2016
Same author

Slipped capital femoral epiphysis: is it worth the risk and cost not to offer prophylactic fixation of the contralateral hip?

The bone & joint journal·2015
Same author

Seasonal variation in the effects of hard substratum biofilming on settlement of marine invertebrate larvae.

Biofouling·2011
Same author

Positioning for elbow fixation in young children.

Annals of the Royal College of Surgeons of England·2011
Same author

Changing incidence of slipped capital femoral epiphysis: a relationship with obesity?

The Journal of bone and joint surgery. British volume·2007
Same journal

Somatic mobility of transposons is explosive and shaped by distinct integration biases in Arabidopsis thaliana.

Genome biology·2026
Same journal

UK Biobank whole-genome sequencing reveals robust contributions of rare variants to complex-trait heritability.

Genome biology·2026
Same journal

A one-week automated genome-wide optical pooled screen using OttoSeq.

Genome biology·2026
Same journal

Integrated lipidomic and transcriptomic profiling of the host response in human malaria.

Genome biology·2026
Same journal

Centromeric satellite expansion drives genome evolution in the snowy owl.

Genome biology·2026
Same journal

Mapping the landscape of allele-specific expression in porcine genomes.

Genome biology·2026
See all related articles

Area of Science:

  • Genomics
  • Systems Biology
  • Bioinformatics

Background:

  • Genome-wide analysis is producing unprecedented volumes of biological data.
  • Existing approaches are insufficient to fully interpret this complex data.
  • Understanding biological pathways is crucial for deciphering life's mechanisms.

Purpose of the Study:

  • To highlight the need for novel interdisciplinary strategies.
  • To outline the conversion of genomic data into biological pathway information.
  • To leverage this information for broader knowledge of life's functions and evolution.

Main Methods:

  • Development of interdisciplinary approaches.
  • Data analysis integrating genomics and pathway information.
  • Knowledge extraction for evolutionary and functional insights.

Related Experiment Videos

Main Results:

  • Transformation of raw genomic data into structured pathway components.
  • Identification of key elements within biological pathways.
  • Generation of insights into general principles of life.

Conclusions:

  • Interdisciplinary approaches are vital for interpreting large-scale genomic data.
  • Converting data into pathway information enhances biological understanding.
  • This approach provides a foundation for studying the evolution and function of life.