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Related Experiment Videos

[Syphilitic spinal cord gumma].

A El Quessar1, R El Hassani, N Chakir

  • 1Service de Neuroradiologie, Hôpital des Spécialités, Rabat, Maroc.

Journal of Neuroradiology = Journal De Neuroradiologie
|December 6, 2000
PubMed
Summary

This case study highlights a rare syphilitic spinal cord gumma presenting as Brown-Sequard syndrome. Prompt diagnosis and penicillin therapy led to successful treatment, emphasizing syphilis as a treatable cause of spinal cord lesions.

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Pathology

Background:

  • Syphilitic gummas of the central nervous system are rare, typically affecting the brain.
  • Spinal cord involvement is exceptionally uncommon, making diagnosis challenging.

Observation:

  • A 25-year-old patient presented with Brown-Sequard syndrome, initially misdiagnosed as multiple sclerosis.
  • Initial imaging (myelography, CT) was normal, and corticosteroid therapy provided temporary improvement.

Findings:

  • Readmission revealed positive syphilis serology in serum and cerebrospinal fluid (CSF).
  • MRI demonstrated a cervical spinal cord lesion at C3 with arachnoiditis.
  • Pathology confirmed the lesion as a syphilitic gumma.

Implications:

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  • This case underscores the importance of considering neurosyphilis in the differential diagnosis of spinal cord lesions.
  • It highlights the novel MR appearance of a spinal cord gumma, previously undescribed.
  • Effective treatment with penicillin demonstrates the curability of this rare condition.