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Adult-onset atopic dermatitis.

M J Bannister1, S Freeman

  • 1Skin and Cancer Foundation Australia, Darlinghurst, New South Wales, Australia. mbannister@bigpond.com.au

The Australasian Journal of Dermatology
|December 6, 2000
PubMed
Summary

Adult-onset atopic dermatitis is a newly identified condition. This study found 9% of patients in a contact dermatitis clinic had adult-onset atopic dermatitis, distinct from contact dermatitis.

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Area of Science:

  • Dermatology
  • Allergology
  • Immunology

Background:

  • Atopic dermatitis (AD) is a chronic inflammatory skin condition.
  • Onset typically occurs in childhood, with adult-onset AD poorly documented.
  • Distinguishing AD from other forms of dermatitis is crucial for effective management.

Purpose of the Study:

  • To investigate the prevalence and characteristics of atopic dermatitis with onset in adulthood.
  • To differentiate adult-onset atopic dermatitis from co-existing contact dermatitis.

Main Methods:

  • Retrospective review of 2604 patients attending a contact dermatitis clinic.
  • Diagnosis of adult-onset atopic dermatitis based on personal/family history of atopy, elevated IgE, and positive skin prick tests.
  • Exclusion of contact factors through negative patch testing.

Main Results:

  • 243 patients (9%) were diagnosed with atopic dermatitis with onset at age 20+.
  • 213 patients (8%) had both atopic dermatitis and contact dermatitis.
  • Adult-onset AD showed a female preponderance and varied age of onset.
  • Common dermatitis sites included generalized involvement, hands, and face.

Conclusions:

  • Adult-onset atopic dermatitis is a distinct clinical entity.
  • It can occur without identifiable contact factors.
  • Further research into the pathogenesis and management of adult-onset AD is warranted.

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