[Long-term follow-up of children with surgically treated primary vesicouretral reflux]

Y Sugita1, S Tanikaze, S Kamidono

  • 1Department of Urology, Kobe Children's Hospital.

Insights

This study on surgically treated primary vesicoureteral reflux found hypertension and proteinuria were rare in patients over 15. Long-term follow-up is crucial for those with severe reflux treated early.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Surgical Outcomes

Background:

  • Primary vesicoureteral reflux (VUR) is a common condition in children.
  • Surgical intervention is a primary treatment for VUR.
  • Long-term renal outcomes after VUR surgery require continued investigation.

Purpose of the Study:

  • To evaluate renal function, hypertension, and proteinuria in adult patients (≥15 years) who underwent surgical treatment for primary VUR.
  • To identify factors influencing renal function post-VUR surgery.

Main Methods:

  • Retrospective review of 22 patients aged 15 and over with surgically treated primary VUR.
  • Assessment of hypertension and proteinuria.
  • Evaluation of renal function using the extraction factor by Heyman's method.
  • Analysis of the relationship between age at operation, reflux grade, and extraction factor.

Main Results:

  • Only one patient presented with proteinuria; no patients had hypertension.
  • The extraction factor tended to increase with older age at operation.
  • The extraction factor tended to decrease with a higher grade of reflux at operation.

Conclusions:

  • Hypertension and proteinuria appear uncommon in adults with a history of surgically treated primary VUR.
  • Severe reflux and early surgical intervention may necessitate extended long-term patient monitoring.
  • The findings underscore the importance of vigilant long-term follow-up for specific patient cohorts post-VUR surgery.

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