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[Postoperative wound infections in elective colorectal surgery]
1Avdeling for tumorbiologi, Det Norske Radiumhospital, Oslo. kjersti.flatmark@labmed.uio.no
Summary
Surgical wound infections in colorectal surgery occurred in 8% of patients. Antimicrobial prophylaxis is effective, with combined anaerobic and aerobic drugs recommended, though no single best regimen is identified.
Area of Science:
- Colorectal surgery
- Surgical site infections
- Antimicrobial prophylaxis
Background:
- Surgical wound infections are a significant challenge in colorectal surgery.
- Elective colorectal surgery at Lillehammer County Hospital was studied.
- Literature review assessed antimicrobial prophylaxis efficacy and preferred regimens.
Purpose of the Study:
- Investigate postoperative wound infection frequency.
- Assess evidence for antimicrobial prophylaxis in colorectal surgery.
- Identify preferred antimicrobial regimens and their impact on infection rates.
Main Methods:
- Prospective follow-up of 99 patients for 14 days post-surgery.
- Wound infection status recorded, with cultures for suspected cases.
- Systematic review of literature focusing on antimicrobial prophylaxis.
Main Results:
- Eight out of 99 patients (8%) developed surgical wound infections.
- Systematic review of 147 studies showed an 11% infection rate with antibiotic prophylaxis.
- No definitive 'gold standard' antimicrobial regimen was identified.
Conclusions:
- The observed surgical wound infection rate aligns with systematic review findings.
- Antimicrobial prophylaxis is well-documented to reduce surgical site infections.
- Combined anaerobic and aerobic antimicrobial agents are recommended; Norwegian studies identified two adequate regimens.