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Related Experiment Videos

[Severe rickets in puberty].

J Fenger-Grøn1

  • 1Paediatrisk afdeling, Kolding Sygehus.

Ugeskrift for Laeger
|December 7, 2000
PubMed
Summary
This summary is machine-generated.

Rickets, a bone disease caused by vitamin D deficiency, can affect adolescents with extreme indoor lifestyles and low dietary intake. Early consideration of rickets is crucial for timely diagnosis and treatment in at-risk youth.

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Area of Science:

  • Pediatrics
  • Endocrinology
  • Nutritional Science

Background:

  • Vitamin D deficiency is a global health concern, particularly in populations with limited sun exposure and inadequate dietary intake.
  • Adolescence is a critical period for bone development, making nutritional deficiencies potentially impactful.
  • Hypocalcemia, a condition of low blood calcium, can result from severe vitamin D deficiency.

Observation:

  • Two adolescent brothers of Palestinian origin presented with symptoms suggestive of a chronic condition.
  • Their lifestyle involved prolonged periods spent indoors, limiting natural sunlight exposure.
  • Dietary assessment revealed a consistently low intake of vitamin D-rich foods.

Findings:

  • The brothers exhibited clinical signs and biochemical evidence of severe hypocalcemia.

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  • Despite debilitating symptoms persisting over time, the diagnosis of rickets was significantly delayed.
  • Diagnostic workup confirmed rickets secondary to profound vitamin D deficiency.

    • Implications:

    • This case highlights the importance of considering rickets in adolescents presenting with unexplained symptoms, especially those with risk factors like indoor lifestyles and poor nutrition.
    • Delayed diagnosis of rickets can lead to long-term skeletal deformities and complications.
    • Healthcare providers should maintain a high index of suspicion for nutritional deficiencies, including vitamin D deficiency, in pediatric and adolescent patients with relevant risk factors.