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Iatrogenic coronary artery dissections extending into and involving the aortic root
D W Dunning1, J K Kahn, E T Hawkins
1Division of Cardiology, Department of Medicine, William Beaumont Hospital, Royal Oak, Michigan, USA.
Insights
Iatrogenic coronary artery dissection extending to the aorta is rare (0.02% incidence). Acute myocardial infarction patients had higher rates. Management varied based on dissection extent.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Vascular Surgery
Background:
- Iatrogenic coronary artery dissection can extend into the aorta, a rare but serious complication.
- Understanding the incidence and characteristics of these dissections is crucial for patient management.
Purpose of the Study:
- To determine the incidence of iatrogenic coronary artery dissection extending into the aorta.
- To characterize the aortic lesions associated with this complication.
Main Methods:
- Retrospective review of 43,143 cardiac catheterizations performed between September 1993 and September 1999.
- Analysis of incidence, patient demographics, and outcomes.
- Histologic examination of tissue samples from affected patients.
Main Results:
- An overall incidence of 0.02% for coronary artery-aortic dissections was found.
- Dissections were more common in patients treated for acute myocardial infarction (0.19% vs. 0.01%).
- Limited dissections were managed with stenting; extensive dissections (>40 mm) required surgery.
Conclusions:
- Iatrogenic coronary artery-aortic dissection is infrequent but associated with higher rates in acute myocardial infarction patients.
- Histologic analysis showed no predisposing pathology beyond age-related changes.
- Treatment strategies should be tailored to the extent of aortic involvement.
Abstract:
We set out to determine the incidence of iatrogenic coronary artery dissection extending into the aorta and to characterize the aortic lesions. We reviewed the data from 43,143 cardiac catheterizations from September 1993 through September 1999 and found 9 coronary artery-aortic dissections for an overall incidence of 0.02%. Four of these patients were undergoing treatment for acute myocardial infarction (AMI) and aortic dissection was more common than for non-AMI patients (0.19% vs. 0.01%, P < 0.0006). Histologic analysis of tissue samples from 2 cases revealed age related changes only and no evidence of predisposing pathology. Patients with limited aortic involvement were successfully managed with stenting of the coronary dissection entry point whereas aortic dissection extending up the aorta >40 mm from the coronary os required surgical intervention.
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