Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Porphyria cutanea tarda.

B P Khoo1, Y K Tay

  • 1Raffles Surgicentre, Singapore.

Singapore Medical Journal
|December 8, 2000
PubMed
Summary
This summary is machine-generated.

Porphyria cutanea tarda (PCT), a rare metabolic disorder, causes blistering on sun-exposed skin due to enzyme deficiencies. Diagnosis involves urine fluorescence, with treatment including chloroquine and venesection.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and descriptive epidemiology of atopic dermatitis and its impact on quality of life in Singapore.

The British journal of dermatology·2017
Same author

Increased risk of strontium ranelate-related SJS/TEN is associated with HLA.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2016
Same author

Danazol-induced Stevens-Johnson syndrome in a patient with systemic lupus erythematosus.

Dermatology online journal·2015
Same author

Building pharmacogenetics into a pharmacovigilance program in Singapore: using serious skin rash as a pilot study.

The pharmacogenomics journal·2014
Same author

AFOMP POLICY STATEMENT No. 2: recommended clinical radiation oncology medical physicist staffing levels in AFOMP countries.

Australasian physical & engineering sciences in medicine·2010
Same author

Stevens-Johnson syndrome and toxic epidermal necrolysis: efficacy of intravenous immunoglobulin and a review of treatment options.

Singapore medical journal·2009
Same journal

Response to comments on: Diagnostic classification of dermatomyositis with and without electrodiagnostic study: real-world clinical practice.

Singapore medical journal·2026
Same journal

Comments on: Diagnostic classification of dermatomyositis with and without electrodiagnostic study: real-world clinical practice.

Singapore medical journal·2026
Same journal

Computed tomographic evaluation of bronchiolitis: unravelling the multifaceted spectrum of airways and pulmonary abnormalities.

Singapore medical journal·2026
Same journal

Approach to facial pain.

Singapore medical journal·2026
Same journal

Glioblastoma: current challenges and future horizons.

Singapore medical journal·2026
Same journal

The role of public health specialists in tertiary hospitals in Singapore.

Singapore medical journal·2026
See all related articles

Area of Science:

  • Biochemistry
  • Dermatology
  • Genetics

Background:

  • Porphyrias are rare metabolic disorders stemming from enzyme deficiencies in the heme biosynthesis pathway.
  • Porphyria cutanea tarda (PCT) is the most prevalent porphyria but infrequently observed in Asian populations.

Observation:

  • A case of PCT is presented in an Asian patient.
  • Clinical presentation included blistering eruptions on sun-exposed skin areas.

Findings:

  • Diagnostic confirmation relies on detecting coral pink fluorescence of uroporphyrins in acidified urine.
  • The underlying cause is a specific enzyme deficiency affecting porphyrin-heme metabolism.

Implications:

  • Highlights the occurrence of PCT in Asian countries, challenging previous assumptions.

Related Experiment Videos

  • Effective treatment strategies include low-dose chloroquine and interval phlebotomy (venesection).
  • Early diagnosis and management are crucial for patients with PCT.