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Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

[A magnetic resonance study of 39 children with different causes of short stature]

G Zuccoli1, F Ferrozzi, A Troiso

  • 1Dipartimento di Diagnostica per Immagini, Arcispedale Santa Maria Nuova, Reggio Emilia. rx@netvalley.it

La Radiologia Medica
|December 8, 2000
PubMed

Insights

Magnetic Resonance Imaging (MRI) is useful for diagnosing growth hormone deficiency in children. Some patients with pituitary hormone deficiencies showed abnormal MRI findings, including small pituitary lobes and ectopic neurohypophysis.

Area of Science:

  • Pediatric Endocrinology
  • Neuroradiology
  • Diagnostic Imaging

Context:

  • Short stature in children can be caused by pituitary hormone deficiencies.
  • Accurate diagnosis is crucial for timely and effective treatment.
  • Magnetic Resonance Imaging (MRI) is a key imaging modality in evaluating the hypothalamo-hypophyseal region.

Purpose:

  • To determine the correlation between Magnetic Resonance (MR) imaging findings and the presence of isolated growth hormone deficiency (IGHD) or multiple pituitary hormone deficiency (MPHD) in children.
  • To assess the diagnostic utility of MRI in pediatric patients with suspected pituitary dysfunction.

Summary:

  • This study analyzed MRI scans of 39 children (mean age 9.6 years) with diagnosed growth hormone deficiency.
  • Abnormalities such as a small anterior pituitary lobe (33%) and ectopic neurohypophysis (20%) were observed.
  • A significant portion of patients (48%) exhibited MR findings consistent with their hormonal deficiencies, highlighting MRI's role.

Impact:

  • MRI findings can aid in the diagnosis and management of pediatric growth hormone deficiency.
  • The study underscores the importance of integrating neuroimaging with laboratory tests for comprehensive pituitary evaluation.
  • Results support the use of MRI as a valuable tool in the diagnostic and therapeutic approach to short stature in children.
Abstract

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