[Aortic stenosis and intestinal blood loss from angiodysplasia: valve replacement is a therapeutic option]

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J P Drenth1, F M Nagengast

  • 1Universitair Medisch Centrum St. Radboud, Kliniek voor Inwendige Ziekten, afd. Maag-, Darm- en Leverziekten, Nijmegen. jphdrenth@compuserve.com

Nederlands Tijdschrift Voor Geneeskunde
|December 8, 2000
PubMed

Insights

Severe aortic stenosis can cause recurrent gastrointestinal bleeding due to angiodysplasia. Treating the aortic valve stenosis resolved anemia in three patients, suggesting a link between these conditions.

Area of Science:

  • Cardiology
  • Gastroenterology
  • Internal Medicine

Background:

  • Recurrent iron deficiency anemia can stem from gastrointestinal bleeding of unknown origin.
  • Angiodysplasias are a recognized cause of obscure gastrointestinal bleeding.
  • A potential association between aortic stenosis and angiodysplasia has been suggested in literature.

Observation:

  • Three male patients (aged 61-68) presented with chronic iron deficiency anemia.
  • Aortic stenosis was diagnosed in all three patients.
  • Colonoscopy revealed angiodysplastic lesions, with suspected additional lesions in the small intestine.

Findings:

  • Despite interventions like surgery and endoscopy, gastrointestinal bleeding persisted.
  • Aortic valve replacement with a bioprosthesis was performed on all patients.
  • Following aortic valve replacement, all patients experienced recovery of hemoglobin levels and resolution of anemia.

Implications:

  • This case series suggests a significant link between aortic stenosis and angiodysplasia-related gastrointestinal bleeding.
  • Resolution of anemia after aortic valve repair highlights the importance of considering cardiac conditions in patients with obscure GI bleeding.
  • Further epidemiological studies are warranted to confirm the association between aortic stenosis and angiodysplasia.

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