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[Hyperaggregation syndrome in patients with osteolytic psoriatic arthritis]
Terapevticheskii Arkhiv
|December 8, 2000
Abstract
Aim:
To study blood rheology in patients with psoriatic arthritis (PA) having local or advanced osteolysis.
Materials And Methods:
The trial included 16 patients with significant PA and clinical and x-ray symptoms of joint surface osteolysis. Kinetics of red cell aggregation and disaggregation was studied in specially designed erythroagregometer.
Results:
The assessment of red cell aggregation indicated the presence of hyperaggregation syndrome in the majority of PA patients with associated osteolysis.
Conclusion:
Hyperaggregation may contribute to bone destruction. Its onset can be reviewed as a risk factor for serious destructive changes in the joints.