Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Gliosarcoma associated with a huge cyst--case report.

M Kurosaki¹, S Taniura, S Tanaka

¹Division of Neurosurgery, Tottori University School of Medicine.

Neurologia Medico-Chirurgica

|December 8, 2000

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hepatitis B surface antigen reduction by switching from long-term nucleoside/nucleotide analogue administration to pegylated interferon.

Journal of viral hepatitis·2017

Same author

Network-guided modeling allows tumor-type independent prediction of sensitivity to all-trans-retinoic acid.

Annals of oncology : official journal of the European Society for Medical Oncology·2016

Same author

Effects of HLA-DPB1 genotypes on chronic hepatitis B infection in Japanese individuals.

Tissue antigens·2015

Same author

A randomized, double-blind, placebo-controlled, phase III trial of erlotinib with or without a c-Met inhibitor tivantinib (ARQ 197) in Asian patients with previously treated stage IIIB/IV nonsquamous nonsmall-cell lung cancer harboring wild-type epidermal growth factor receptor (ATTENTION study).

Annals of oncology : official journal of the European Society for Medical Oncology·2015

Same author

ITPA genetic variants influence efficacy of PEG-IFN/RBV therapy in older patients infected with HCV genotype 1 and favourable IL28B type.

Journal of viral hepatitis·2014

Same author

Noninvasive estimation of fibrosis progression overtime using the FIB-4 index in chronic hepatitis C.

Journal of viral hepatitis·2012

This case highlights a rare cystic gliosarcoma, a brain tumor difficult to diagnose preoperatively due to imaging resembling low-grade gliomas. Early surgical intervention and adjuvant therapy are crucial for managing this aggressive tumor.

Area of Science:

Neuro-oncology
Surgical Pathology

Background:

Gliosarcoma is a rare and aggressive primary brain tumor, a variant of glioblastoma, characterized by both glial and sarcomatous components.
Large cystic components are uncommon in gliosarcoma, making preoperative diagnosis challenging.

Observation:

A 55-year-old female presented with neurological deficits suggestive of a large brain mass.
Imaging revealed a large cystic lesion with an enhancing mural nodule in the right frontal lobe.
Histopathological examination confirmed gliosarcoma following surgical resection.

Findings:

The tumor exhibited significant cystic degeneration, mimicking cystic low-grade gliomas on initial neuroradiological assessment.
Recurrence necessitated a second surgery, followed by adjuvant radiation therapy and chemotherapy.

Related Experiment Videos

Complete resection and multimodal treatment were performed for tumor regrowth.

Implications:

This case underscores the importance of considering gliosarcoma in the differential diagnosis of large cystic brain tumors, especially when imaging is atypical.
Aggressive surgical management combined with adjuvant therapies is essential for improving outcomes in patients with cystic gliosarcoma.
Further research into the specific radiological features and optimal treatment strategies for cystic gliosarcoma is warranted.