Primary central nervous system immunocytoma: MRI and spectroscopy

Area of Science:

• Neuro-oncology
• Neuroradiology
• Neuropathology

Background:

• Primary cerebral lymphomas (PCNSL) are typically aggressive B-cell tumors.
• Limited data exists on the clinical, imaging, and spectroscopy of rare PCNSL subtypes.
• Immunocytoma represents a rare subtype of PCNSL.

Observation:

• A young woman presented with a primary cerebral immunocytoma.
• MRI revealed a radially enhancing tumor with minimal perifocal edema.
• MR spectroscopy suggested a low cellular turnover rate.

Findings:

• The tumor exhibited slow clinical progression.
• Imaging and spectroscopy findings were consistent with a low-grade malignancy.
• The patient showed no significant changes with treatment.

Implications:

• This case expands understanding of rare PCNSL subtypes.
• Highlights the importance of integrating clinical, imaging, and spectroscopy data for diagnosis.
• Suggests that some primary cerebral immunocytomas may follow an indolent course.