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Bovine spongiform encephalopathy: an overview.

L A Detwiler1, R Rubenstein

  • 1USDA, APHIS, Veterinary Services, Robbinsville, New Jersey 08691, USA.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|December 8, 2000
PubMed
Summary

Bovine spongiform encephalopathy (BSE), or mad cow disease, is a fatal neurological illness in cattle. Over 180,000 cases have been reported globally, primarily impacting the UK livestock industry.

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Area of Science:

  • Veterinary Neurology
  • Epidemiology of Livestock Diseases

Background:

  • Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is a chronic, fatal, neurodegenerative prion disease.
  • First diagnosed in Great Britain in 1986, BSE has significantly impacted the global livestock industry, particularly in the UK.

Purpose of the Study:

  • To provide an overview of Bovine spongiform encephalopathy (BSE) epidemiology.
  • To detail the geographical distribution and historical prevalence of BSE cases worldwide.

Main Methods:

  • Review of global case data for Bovine spongiform encephalopathy (BSE) since its initial diagnosis.
  • Analysis of geographical distribution and incidence of BSE in affected countries.

Main Results:

  • Over 180,000 cases of BSE have been recorded globally since 1986.
  • The United Kingdom accounts for over 95% of all reported BSE cases.
  • BSE has been confirmed in cattle in several European countries, including France, Ireland, and Switzerland.

Conclusions:

  • Bovine spongiform encephalopathy (BSE) represents a significant historical challenge to the UK livestock sector.
  • While BSE has been detected in multiple European nations, its prevalence remains overwhelmingly concentrated in the United Kingdom.
  • Current data indicates no known cases of BSE in the United States.

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