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Published on: November 17, 2016
Late onset diffuse lamellar keratitis associated with an epithelial defect in six eyes
1Department of Ophthalmology, Stanford University School of Medicine, CA 94305, USA.
Purpose:
To report six cases of late onset diffuse lamellar keratitis associated with epithelial defects 2 to 12 months following uncomplicated laser in situ keratomileusis (LASIK).
Methods:
Retrospective case series.
Results:
The interface inflammation and epithelial defects were treated aggressively with topical corticosteroids and topical antibiotics with complete resolution over 1 to 2 weeks. There were no complications or loss of best spectacle-corrected visual acuity. These cases illustrate new understanding in the etiology of diffuse lamellar keratitis following lamellar surgery.
Conclusion:
Late onset diffuse lamellar keratitis in association with epithelial defects may occur following LASIK. Treatment with topical antibiotics and topical corticosteroids may result in uncomplicated, complete resolution.

