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Descending aorta wall volume and coronary artery disease: a comparative study using enhanced computed tomography of

R Yamamoto1, J Takasu, K Yokoyama

  • 1Third Department of Internal Medicine, Chiba University School of Medicine, Chiba City, Japan.

Japanese Circulation Journal
|December 8, 2000
PubMed

Insights

Aortic wall volume measured by CT angiography is linked to coronary artery disease. Increased aortic wall volume indicates a higher likelihood of significant coronary artery stenosis, aiding in diagnosis.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Atherosclerosis Research

Background:

  • Coronary artery disease (CAD) diagnosis relies on invasive angiography.
  • Non-invasive imaging methods to assess atherosclerosis burden are needed.
  • Aortic wall volume (AWV) is a potential marker for systemic atherosclerosis.

Purpose of the Study:

  • To investigate the association between aortic wall volume (AWV) and coronary artery atherosclerosis.
  • To determine if AWV can serve as a non-invasive predictor of coronary artery disease.

Main Methods:

  • Enhanced computed tomography (CT) was used to measure AWV in a 7-cm segment of the descending thoracic aorta.
  • Coronary artery atherosclerosis was quantified using Gensini score (stenosis severity) and Extent score (involvement severity) via angiography.
  • 180 patients were included in the study.

Main Results:

  • Mean AWV was significantly higher in patients with significant coronary artery stenosis (9.83 cm3) compared to those without (8.09 cm3).
  • AWV was an independent predictor of significant coronary artery disease and high Extent score (>=60).
  • Calcification of AWV did not correlate with coronary atherosclerosis.

Conclusions:

  • Quantification of aortic atherosclerosis via AWV is a valuable tool for diagnosing coronary artery disease.
  • AWV may serve as a useful non-invasive biomarker for assessing the risk of coronary artery disease.

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