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Updated: Sep 5, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Insights
Recognizing warning signs in patients with intracranial aneurysms is crucial. Early detection can help prevent devastating major hemorrhages, improving patient outcomes.
Area of Science:
- Neurology
- Neurosurgery
- Vascular Neurology
Background:
- Intracranial aneurysms pose a significant risk of major hemorrhage.
- Identifying warning signs is critical for timely intervention.
Purpose of the Study:
- To analyze warning signs preceding major hemorrhage in patients with intracranial aneurysms.
- To determine the interval between warning signs and major hemorrhage based on aneurysm location.
Main Methods:
- Retrospective analysis of 192 patients diagnosed with intracranial aneurysms.
- Evaluation of warning signs and their temporal relationship to major hemorrhage.
- Categorization of data based on aneurysm location.
Main Results:
- 59% of patients (113 out of 192) experienced warning signs before major hemorrhage.
- The interval from warning signs to hemorrhage varied by aneurysm location: 16.9 days (anterior communicating/cerebral), 6 days (middle cerebral), and 7.3 days (intradural internal carotid).
- Aneurysm location significantly influenced the incidence of warning signs.
Conclusions:
- Early recognition of warning signs in intracranial aneurysms is vital.
- Understanding the time intervals associated with different aneurysm locations can aid in clinical management.
- Prompt identification of warning signs may mitigate the severe consequences of major hemorrhage.
Abstract:
Warning signs preceding major hemorrhage were analyzed in 192 patients with intracranial aneurysms. One hundred and thirteen (59 percent) had warning signs. The average interval between the last warning signs and the major attacks was 16.9 ddays with anterior communicating and anterior cerebral aneurysms, 6 days with middle cerebral aneurysms, and 7.3 days with intradural internal carotid aneurysms. The incidence was much higher in aneurysms (69 percent) and with location of the aneurysms. Early recognition of warning signs may protect patients from the devasting effects of major hemmorhage.
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