Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Surface treated catheters with ion beam based process for blood access.

R Bambauer1, P Mestres, R Schiel

  • 1Institute for Blood Purification, University of Saarland, Homburg/Saar, Germany.

Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis
|December 9, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in Quality of Diabetes Care and Morbidity over 20 Years in People with Type 1 Diabetes and Long Diabetes Duration: The JEVIN Trial.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association·2016
Same author

Use and Effectiveness of Continuous Subcutaneous Insulin Infusion (CSII) and Multiple Daily Insulin Injection Therapy (MIT) in Children, Adolescents and Young Adults with Type 1 Diabetes Mellitus.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association·2016
Same author

[Experimental corneal imaging and corneal surgery with non-amplified femtosecond laser pulses].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2012
Same author

An innovative telemedical support system to measure physical activity in children and adolescents with type 1 diabetes mellitus.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association·2011
Same author

[Femtosecond laser ablation and scanning microscopy of the internal retinal limiting membrane: an experimental study].

Vestnik oftalmologii·2009
Same author

Efficacy, safety and tolerability of valsartan 80 mg compared to irbesartan 150 mg in hypertensive patients on long-term hemodialysis (VALID study).

Clinical nephrology·2008

Silver coatings on large bore catheters significantly reduce bacterial colonization and thrombogenicity. This surface treatment offers improved resistance to infection and thrombus formation in blood-contacting devices.

Area of Science:

  • Biomaterials Science
  • Medical Device Engineering
  • Infectious Disease Research

Background:

  • Blood-contacting catheters frequently lead to complications like infection, thrombosis, and stenosis.
  • These issues are often linked to the surface properties of the catheter material.
  • Surface modification techniques, including ion implantation and ion beam assisted deposition (IBAD) with silver, can mitigate these complications without altering bulk material properties.

Purpose of the Study:

  • To evaluate the efficacy of silver-coated, large-bore catheters in preventing complications during extracorporeal detoxification.
  • To assess the impact of surface treatment on bacterial colonization and thrombogenicity.

Main Methods:

  • A prospective study involving 135 patients and 170 large-bore catheters (internal jugular or subclavian veins).

Related Experiment Videos

  • Comparison of 78 surface-treated (silver-coated) catheters against 92 untreated control catheters.
  • Post-removal analysis included standard microbiologic assays for bacterial colonization and scanning electron microscopy (SEM) for thrombogenicity assessment.

    • Main Results:

    • Bacterial colonization was significantly lower in treated catheters (7%) compared to untreated controls (35.3%).
    • SEM analysis revealed that all silver-coated catheters exhibited low thrombogenicity.
    • The surface treatment affected only the near-surface region, preserving bulk material properties.

    Conclusions:

    • Ion beam-based silver coating processes effectively enhance the resistance of blood-contacting catheters to thrombus formation and infection.
    • Surface-modified catheters demonstrate improved safety and performance in clinical applications like extracorporeal detoxification.