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Allo-tolerance and allorejection responses ex vivo
1Department of Surgery, University of Cambridge, Addenbrookes Hospital, UK.
Abstract:
Spleen cells from fully immune competent mice show different intracellular STAT responses to alloantigen. Cells from mice primed to accept the alloantigen have low STAT 6 and fragmented STAT 4, compared to cells from mice primed to reject the same alloantigen.