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Updated: Aug 1, 2026
10:19
Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
Ultrasound-guided fine-needle aspiration and thyroid disease
K A Newkirk1, M D Ringel, J Jelinek
1Department of Otolaryngology--Head and Neck Surgery, Georgetown University Medical Center, Washington, DC 20007, USA.
Summary
Ultrasound-guided fine-needle aspiration (USGFNA) is a safe and effective diagnostic tool for thyroid nodules. This method accurately diagnoses thyroid disease, particularly for nodules that are difficult to palpate.
Area of Science:
- Endocrinology
- Oncology
- Radiology
Background:
- Fine-needle aspiration (FNA) is crucial for thyroid disease management.
- Ultrasound-guided FNA (USGFNA) utilization has increased.
- Accurate diagnosis impacts patient treatment strategies.
Purpose of the Study:
- To evaluate the diagnostic efficacy and safety of USGFNA.
- To determine the performance metrics of USGFNA for thyroid nodules.
- To assess cancer yield and complication rates associated with USGFNA.
Main Methods:
- Retrospective chart review of patients undergoing USGFNA.
- Analysis of 234 procedures on 215 patients over 2.5 years.
- Inclusion of data on nodule characteristics and procedural outcomes.
Main Results:
- The study included patients with an average nodule size of 2.1 cm.
- USGFNA demonstrated high sensitivity (88.2%) and specificity (80.0%).
- Cancer yield was 44%, with inadequacy at 10.5% and complications at 8.5%.
Conclusions:
- USGFNA is a safe and effective diagnostic method for thyroid disease.
- It is particularly valuable for managing difficult-to-palpate thyroid nodules.
- USGFNA provides accurate diagnostic information for thyroid nodule assessment.
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