A therapeutic target and biomarker in Friedreich's ataxia

LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease.

Human molecular genetics·2017

LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease.

Free radical research·2015

Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease.

Neurobiology of disease·2014

Gene-environment interactions in Parkinson's disease: the importance of animal modeling.

Clinical pharmacology and therapeutics·2010

Sequential and concerted gene expression changes in a chronic in vitro model of parkinsonism.

Neuroscience·2008

Ethyl-EPA in Huntington disease: a double-blind, randomized, placebo-controlled trial.

Neurology·2005

Carotid Artery Stenting Is Now an Evidence-Based Adjunct to Intensive Medical Therapy for Stroke Prevention.

Neurology·2026

Autonomic Network Signatures of Interictal Cardiorespiratory Dysfunction in Patients With Temporal Lobe Epilepsy.

Neurology·2026

Evaluation of Disease Severity Using CSF Biomarkers in Patients With Probable Cerebral Amyloid Angiopathy.

Neurology·2026

Repairing the Amyotrophic Lateral Sclerosis Trial Credibility Gap.

Neurology·2026

Association Between Immigration Status and the Intensity of Acute Stroke Care in Ontario, Canada: A Retrospective Study.

Neurology·2026

Gestational Changes in Antiseizure Medication Concentrations and the Impact of Polytherapy: A Prospective Multicenter Cohort Study in China.

Neurology·2026

Development and evaluation of lecithin-based andrographolide liposomal nanoparticles: pharmacokinetics and anti-inflammatory activity in a mouse model of house dust mite-induced allergic lung inflammation.

The Journal of pharmacy and pharmacology·2026

Real-world effectiveness of abrocitinib and upadacitinib in atopic dermatitis: a propensity-matched analysis.

The Journal of dermatological treatment·2026

Efficacy and Safety of Ultra-Low Starting Dose Febuxostat Titration in Male Patients With Primary Gout.

International journal of rheumatic diseases·2026

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A therapeutic target and biomarker in Friedreich's ataxia

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LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson's disease.

LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease.

Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease.

Gene-environment interactions in Parkinson's disease: the importance of animal modeling.

Sequential and concerted gene expression changes in a chronic in vitro model of parkinsonism.

Ethyl-EPA in Huntington disease: a double-blind, randomized, placebo-controlled trial.

Carotid Artery Stenting Is Now an Evidence-Based Adjunct to Intensive Medical Therapy for Stroke Prevention.

Autonomic Network Signatures of Interictal Cardiorespiratory Dysfunction in Patients With Temporal Lobe Epilepsy.

Evaluation of Disease Severity Using CSF Biomarkers in Patients With Probable Cerebral Amyloid Angiopathy.

Repairing the Amyotrophic Lateral Sclerosis Trial Credibility Gap.

Association Between Immigration Status and the Intensity of Acute Stroke Care in Ontario, Canada: A Retrospective Study.

Gestational Changes in Antiseizure Medication Concentrations and the Impact of Polytherapy: A Prospective Multicenter Cohort Study in China.

Development and evaluation of lecithin-based andrographolide liposomal nanoparticles: pharmacokinetics and anti-inflammatory activity in a mouse model of house dust mite-induced allergic lung inflammation.

Real-world effectiveness of abrocitinib and upadacitinib in atopic dermatitis: a propensity-matched analysis.

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A therapeutic target and biomarker in Friedreich's ataxia

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