Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Brain hypoxia, minimal brain dysfunction, and schizophrenia.

The American Journal of Psychiatry

|February 1, 1975

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The relationship of HIV status, type of coagulation disorder, and school absenteeism to cognition, educational performance, mood, and behavior of boys with hemophilia.

The Journal of genetic psychology·1996

Same author

Blood product use by hemophiliacs in relation to AIDS risk awareness and patient variables.

Psychosomatics·1994

Same author

Sexual practices and AIDS knowledge among women partners of HIV-infected hemophiliacs.

Public health reports (Washington, D.C. : 1974)·1992

Same author

Rumination disorder: differential diagnosis.

Journal of the American Academy of Child and Adolescent Psychiatry·1988

Same author

Parent attitudes and child personality traits in hemophilia: a six-year longitudinal study.

International journal of psychiatry in medicine·1988

Same author

Personality traits of hemophilic boys.

Journal of developmental and behavioral pediatrics : JDBP·1986

Same journal

2026 Annual Meeting: President-Elect Address.

The American journal of psychiatry·2026

Same journal

2026 Annual Meeting: CEO and Medical Director's Address.

The American journal of psychiatry·2026

Same journal

Reports to the Membership.

The American journal of psychiatry·2026

Same journal

Convergent Metabolic Dysregulations But Divergent Contributing Pathways Across Severe Mental Disorders: The Power of Combining Genetics and Metabolomics.

The American journal of psychiatry·2026

Same journal

2026 Annual Meeting: Presidential Address.

The American journal of psychiatry·2026

Same journal

Represcribing Previously Used Antipsychotics: Response to So.

The American journal of psychiatry·2026

See all related articles

Brain hypoxia during early development may increase the risk of minimal brain dysfunction (MBD) and adult schizophrenia. Early intervention and multidisciplinary care are crucial for affected children and families.

Area of Science:

Neuroscience
Developmental Psychology
Psychiatry

Background:

Brain hypoxia, a condition of insufficient oxygen to the brain, can occur during prenatal, perinatal, or early postnatal periods.
Minimal brain dysfunction (MBD) is a term often used to describe subtle neurological deficits affecting learning, behavior, and attention.
Schizophrenia is a severe mental disorder characterized by distortions in thought, perception, and emotion.

Purpose of the Study:

To propose a hypothesis linking early life brain hypoxia to the later development of minimal brain dysfunction and schizophrenia.
To highlight the potential at-risk population for these conditions.

Main Methods:

This study is based on a hypothesis, not empirical data collection.
It involves a theoretical framework connecting early neurological insult to later psychiatric and neurodevelopmental outcomes.

Related Experiment Videos

Main Results:

The hypothesis posits a direct correlation between early brain hypoxia and increased risk for MBD and schizophrenia.
Individuals experiencing hypoxic events in early life are identified as a vulnerable group.

Conclusions:

The proposed hypothesis has significant implications for early identification and intervention strategies for children with MBD.
It underscores the importance of multidisciplinary management approaches for these children throughout their developmental trajectory.