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Early voiding dysfunction associated with prostate brachytherapy.

Wagner1, Nag, Young

  • 1Division of Urologic Surgery, The Ohio State University, 456 West 10th Ave., 43210-1228, Columbus, OH, USA

Urologic Oncology
|December 13, 2000
PubMed
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Transperineal prostate brachytherapy can cause temporary urinary retention in 15% of patients. International Prostate Symptom Scores significantly increase post-procedure but typically resolve, necessitating patient education.

Area of Science:

  • Urology
  • Oncology
  • Radiation Oncology

Background:

  • Transperineal prostate brachytherapy is increasingly used for localized prostate cancer.
  • Prospective data on early complications, specifically voiding dysfunction, is limited.

Purpose of the Study:

  • To analyze early voiding dysfunction following transperineal prostate brachytherapy.
  • To evaluate International Prostate Symptom Score (IPSS) changes and morbidity.

Main Methods:

  • Prospective evaluation of 46 patients undergoing Palladium-103 brachytherapy.
  • Administration of IPSS questionnaires preoperatively and at two postoperative visits.
  • Statistical analysis of total IPSS, individual components, and bother scores.

Main Results:

Related Experiment Videos

  • Urinary retention occurred in 15% of patients (7/46), with most resolving spontaneously.
  • Mean IPSS increased significantly from 7.1 preoperatively to 20.0 postoperatively (p<0.001).
  • IPSS returned to near baseline (8.0) by the second postoperative visit.

Conclusions:

  • Transperineal prostate brachytherapy is associated with a 15% rate of urinary retention and significant, yet self-limited, increases in voiding symptoms.
  • Pre-procedure patient education regarding potential voiding dysfunction is crucial.