Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Porphyria cutanea tarda affecting lower lip.

A Martínez1, R Morales, U Brethauer

  • 1Department of Oral Pathology, School of Dentistry, University of Concepción, Chile.

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
|December 13, 2000
PubMed
Summary

Porphyria cutanea tarda, a common porphyria, causes sun-sensitive skin blisters. This case highlights lower lip porphyria mimicking actinic cheilitis in a patient with a history of Hodgkin

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel entorhinal projection to the rat dentate gyrus: direct innervation of proximal dendrites and cell bodies of granule cells and GABAergic neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience·1996
Same author

Diagnostic utility of K-ras mutations in fine-needle aspirates of pancreatic masses.

Gastroenterology·1996
Same author

Mutational analysis and secondary structure model of the RNP1-like sequence motif of transcription termination factor Rho.

Journal of molecular biology·1996
Same author

Residues in the RNP1-like sequence motif of Rho protein are involved in RNA-binding affinity and discrimination.

Journal of molecular biology·1996
Same author

Effects of continuous low-dose-rate brachytherapy on the rectum of the rat.

Radiation research·1996
Same author

Efficacy of epiroprim (Ro11-8958), a new dihydrofolate reductase inhibitor, in the treatment of acute Toxoplasma infection in mice.

The American journal of tropical medicine and hygiene·1996

Area of Science:

  • Dermatology
  • Hepatology
  • Genetics

Background:

  • Porphyria cutanea tarda (PCT) is the most prevalent form of porphyria, characterized by photosensitivity and blistering skin lesions.
  • PCT arises from uroporphyrinogen decarboxylase (UROD) deficiency, leading to the accumulation of porphyrins.
  • Risk factors include iron overload, hepatitis C, and alcohol consumption.

Observation:

  • A 62-year-old male patient presented with lower lip lesions.
  • The lesions clinically resembled actinic cheilitis, a sun-induced lip inflammation.
  • The patient had a past medical history of Hodgkin's lymphoma.

Findings:

  • The case report details a diagnosis of porphyria cutanea tarda localized to the lower lip.
  • This presentation mimicked actinic cheilitis, posing a diagnostic challenge.

Related Experiment Videos

  • The patient's history of Hodgkin's lymphoma was noted.

    • Implications:

    • This case underscores the importance of considering porphyria cutanea tarda in the differential diagnosis of lower lip lesions, even when they mimic other conditions.
    • Early and accurate diagnosis of PCT is crucial for appropriate management and preventing complications.
    • Further research may elucidate the specific associations between hematological malignancies like Hodgkin's lymphoma and atypical presentations of PCT.