The pathologist's view point. Part II --aggressive lymphomas
Related Experiment Video
Updated: Oct 10, 2026
Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
S A Pileri1, S Ascani, E Sabattini
1Service of Pathologic Anatomy and Hematopathology, Institute of Hematology and Oncology L. & A. Seràgnoli, Bologna University, Policlinico S. Orsola, Italy. pileri@almadns.unibo.it
Background And Objectives:
The REAL/WHO classification constitutes a new tool for the better understanding and treatment of malignant lymphomas. The authors focus on the key features of aggressive B- and T-cell lymphomas, aiming to contribute to the cross-talk between pathologists and clinicians.
Data Sources And Methods:
Each lymphoma entity is analyzed on the basis of the most representative contributions in the literature and the authors' experience gained in studying more than 20,000 lymphoid tumors over a 20-year period.
Results:
Guidelines for diagnosis and areas of interest for future clinico-pathologic studies are identified and discussed. Within this context, selected data obtained by the application of novel markers are presented.
Interpretation And Conclusions:
The present know- ledge and organization of malignant lymphomas now make the development of tailored therapies a feasible goal.
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