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Ocular involvement in disseminated intravascular coagulopathy
Archives of Ophthalmology (Chicago, Ill. : 1960)
|January 1, 1975
Summary
Disseminated intravascular coagulopathy causes significant ocular pathology, including retinal detachments and choroidal hemorrhage. Key findings reveal thrombotic occlusion in the choriocapillaris and surrounding vessels, affecting vision symmetrically.
Area of Science:
- Ophthalmology
- Hematology
- Pathology
Background:
- Disseminated intravascular coagulopathy (DIC) is a complex hematological disorder.
- Ocular manifestations of DIC are not well-documented.
- Understanding DIC's impact on the eye is crucial for patient management.
Purpose of the Study:
- To illustrate the ocular pathology associated with disseminated intravascular coagulopathy.
- To correlate ophthalmic findings with clinical symptoms in DIC patients.
- To detail the specific vascular changes in the eyes of DIC patients.
Main Methods:
- Case series review of seven patients with DIC.
- Ophthalmic examination and pathological correlation.
- Analysis of clinical manifestations alongside ocular findings.
Main Results:
- Identified retinal detachments and pigment epithelium vacuolar disruption.
- Observed choroidal hemorrhage and symmetrical ocular changes.
- Confirmed thrombotic occlusion of choriocapillaris and adjacent vessels in critical eye regions.
Conclusions:
- DIC leads to characteristic and symmetrical ocular pathologies.
- Thrombotic occlusion of retinal and choroidal vasculature is a key feature.
- Ocular findings provide insights into the systemic effects of DIC.